Questions tagged [us]
What is the role of genetic testing in identifying dogs prone to immune-mediated diseases?
Category: Genetics
Genetic testing plays a significant role in identifying dogs that may be prone to immune-mediated diseases, which are conditions where the immune system mistakenly attacks the body's own tissues. These diseases can range from autoimmune disorders like lupus or pemphigus to immune-mediated hemolytic ...
How can DNA analysis help identify dogs with a predisposition to muscle atrophy?
Category: Genetics
DNA analysis can be a powerful tool in identifying dogs with a predisposition to muscle atrophy, a condition characterized by the weakening and wasting of muscle tissue. This process involves examining a dog's genetic makeup to detect specific mutations or markers associated with inherited muscle di...
What are the genetic causes of dilated cardiomyopathy in dogs?
Category: Genetics
Dilated cardiomyopathy (DCM) in dogs is a serious heart condition characterized by the enlargement and weakening of the heart muscle, leading to reduced cardiac function. While the exact causes of DCM can be multifactorial, including nutritional, environmental, and infectious factors, genetic predis...
What are the genetic causes of portosystemic shunts in dogs?
Category: Genetics
Portosystemic shunts (PSS) in dogs are abnormal blood vessels that allow blood to bypass the liver, leading to a range of health issues. These shunts can be congenital (present at birth) or acquired later in life. The genetic causes of congenital portosystemic shunts are complex and not yet fully un...
What are the genetic causes of hypertrophic osteodystrophy in dogs?
Category: Genetics
Hypertrophic osteodystrophy (HOD) is a painful bone disease that primarily affects young, rapidly growing large and giant breed dogs. While the exact genetic causes of HOD are not fully understood, research suggests that it is a multifactorial condition influenced by both genetic and environmental f...
What are the genetic causes of osteosarcoma in dogs?
Category: Genetics
Osteosarcoma is a highly aggressive and malignant bone tumor that commonly affects dogs, particularly large and giant breeds. Understanding the genetic causes of osteosarcoma in dogs is crucial for both prevention and treatment. While the exact genetic mechanisms are still being studied, several fac...
What are the genetic causes of lymphoma in dogs?
Category: Genetics
Lymphoma, also known as lymphosarcoma, is one of the most common cancers in dogs, accounting for approximately 7-24% of all canine cancers. It is a type of cancer that originates in the lymphocytes, which are white blood cells that play a critical role in the immune system. While the exact causes of...
What are the genetic factors behind hydrocephalus in dogs?
Category: Genetics
Hydrocephalus in dogs is a condition characterized by the accumulation of cerebrospinal fluid (CSF) within the brain's ventricles, leading to increased intracranial pressure and potential brain damage. Genetic factors play a significant role in the development of hydrocephalus, particularly in certa...
What are the genetic causes of histiocytic sarcoma in dogs?
Category: Genetics
Histiocytic sarcoma in dogs is a rare and aggressive form of cancer that originates from histiocytes, which are immune cells involved in the body's defense mechanisms. The genetic causes of this disease are complex and not yet fully understood, but research has identified several genetic factors and...
What are the genetic factors behind myasthenia gravis in dogs?
Category: Genetics
Myasthenia gravis in dogs is a neuromuscular disorder that affects the communication between nerves and muscles, leading to muscle weakness and fatigue. The condition can be congenital (present at birth) or acquired later in life. While the acquired form is more common and often linked to autoimmune...